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AXYS - The Association for X&Y Chromosome Variations
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Monthly Archives: May 2020

Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies

Article Title: Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies

Authors: Green, Flash, and Reiss

Date of Publication: January 2019

“The study of individuals with sex chromosome aneuploidies provides a promising framework for studying sexual dimorphism in neurodevelopmental and psychiatric disorders. Here we will review and contrast four syndromes caused by variation in the number of sex chromosomes: Turner syndrome, Klinefelter syndrome, XYY syndrome, and XXX syndrome. Overall we describe an increased rate of attention deficit hyperactivity disorder and autism spectrum disorder, along with the increased rates of major depressive disorder and anxiety disorders in one or more of these conditions. In addition to contributing unique insights about sexual dimorphism in neuropsychiatric disorders, awareness of the increased risk of neurodevelopmental and psychiatric disorders in sex chromosome aneuploidies can inform appropriate management of these common genetic disorders.”

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Neuropsychological functions, sleep, and mental health in adults with Klinefelter syndrome

Article Title: Neuropsychological functions, sleep, and mental health in adults with Klinefelter syndrome

Authors: Fjermestad, Huster,  Thunberg, Stokke, Gravholt, and Solbakk

Date of Publication: April 29, 2020

“Altogether, men with KS display problems in neuropsychological functions and mental health but do not appear different from controls on most sleep parameters. Our findings indicate that relations between neuropsychological functions, sleep, and mental health differ between men with KS and controls.”

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2020-05-25T14:56:13-04:00Categories: 47,XXY (Klinefelter)|Tags: |
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