Article Title: Quantifying the Spectrum of Early Motor and Language Milestones in Sex Chromosome Trisomy
Authors: Thompson, Bothwell, Janusz, Wilson, Howell, Davis, Swenson, Martin, Kowal, Ikomi, Despradel, Ross, and Tartaglia
Date of Publication: November 2025
“As increasing numbers of infants with prenatal SCT diagnoses present at pediatric practices, we provide an evidence-based schedule of milestone achievement in SCT as a tool for pediatricians and families. Detailed data on SCT milestones can support clinical interpretation of milestone achievement. Increased variability and later median age of milestone acquisition in SCT compared with norms support consideration of all infants with SCT as high risk.”