47,XXY (Klinefelter)

/47,XXY (Klinefelter)

Exploring Klinefelter Syndrome

"The Impact of Living with Klinefelter Syndrome: A Qualitative Exploration of Adolescents and Adults" — This research article examines the medical, psychological, and social challenges that arise in individuals with 47,XXY as well as providing practical recommendations for parents and professionals on how to meet these challenges. Click here.

November 22nd, 2016|

A Klinefelter Update for Pediatricians

"Advances in the Interdisciplinary Care of Children with Klinefelter Syndrome"—This nearly 30-page story in the journal Advances in Pediatrics is directed at pediatricians and family physicians who treat children, and who may thus come across patients with Klinefelter syndrome. It alerts them to the risks the condition carries for neurodevelopmental and psychological complications, and suggests [...]

October 31st, 2016|

The Challenges of Klinefelter’s

"The Klinefelter Syndrome: Current Management and Research Challenges"—From the scientific journal, Andrology, this article summarizes the concluding “Round Table Discussion” of the 2nd International Workshop on the Klinefelter Syndrome in Munster, Germany, March, 2016. Topics include syndrome characteristics, centers of competence for diagnosis and treatment, counseling, support groups, early screening, fertility, testosterone treatment, and basic [...]

October 31st, 2016|

An Extra X or Y Chromosome: Contrasting the Cognitive and Motor Phenotypes in Childhood in Boys with 47,XYY Syndrome or 47,XXY Klinefelter Syndrome

This is a scholarly article by Judith L. Ross, Martha P.D. Zeger, Harvey Kushner, Andrew R. Zinn, and David P. Roeltgen. Read the entire article. From the abstract: "Objective—The goal of this study was to contrast the cognitive phenotypes in boys with 47,XYY (XYY) karyotype and boys with 47,XXY karyotype (Klinefelter syndrome, KS), who share [...]

October 29th, 2016|

Neurocognitive research on 47,XXY

To me, this is one of the "gold standard" research articles on 47,xxy neurocognitive implications. It contains pretty intense medical terminology but it would be recognized as excellent resource/reference material by physicians, educators, the courts, etc. It should help parents and others understand there are absolutely biological issues involved with potential problem behaviors that may [...]

October 28th, 2016|

Comparing 47,XXY and 47,XYY boys

Here is a good research article on comparing the similarities and differences in boys with 47,XXY and 47,XYY from a neurocognitive testing standpoint. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876236/

October 28th, 2016|

Complexities of Hypogonadism

June 30, 2011 http://www.imt.ie/clinical/2011/06/the-complexities-of-hypogonadism.html   Dr. Poochellam Muthalagu looks the primary and secondary reasons for hypogonadism and examines the different treatments available in this country. Male hypogonadism is a clinical syndrome defined by low testosterone levels associated with sexual dysfunction, particularly diminished libido, mood disturbances, reduced lean body mass and increased adipose tissue mass. A [...]

October 28th, 2016|

Klinefelter Syndrome and Other Sex Chromosomal Aneuploidies

The term Klinefelter syndrome (KS) describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY. XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in 500 males. Other sex chromosomal aneuploidies have also been described, although [...]

October 28th, 2016|

Bone Density

We rarely use Wikipedia as a resource, but this overview on bone density is quite well done. As with any medical issue or question, please consult your physician. The Wikipedia entry is a general discussion of the topic. It is not specifically related to X and Y Chromosome Variations. For individuals who are 47,XXY, untreated [...]

October 28th, 2016|

Gender Considerations with 47,XXY

Click here for full article Thinking outside the square: considering gender in Klinefelter syndrome and 47, XXY International Journal of Andrology ェ 2011 European Academy of Andrology, 1–2 http://www.ncbi.nlm.nih.gov/pubmed/21453406 A common genetic condition affecting males, Klinefelter syndrome (KS), is often described as ‘The Forgotten Syndrome’.Although the prevalence of KS has been estimated to be as [...]

October 27th, 2016|