Early Intervention Archives - The Association for X and Y Chromosome Variations

Early Preventive Intervention for Young Children With Sex Chromosome Trisomies (XXX, XXY, XYY)

Article Title: Early Preventive Intervention for Young Children With Sex Chromosome Trisomies (XXX, XXY, XYY): Supporting Social Cognitive Development Using a Neurocognitive Training Program Targeting Facial Emotion Understanding

Authors: Bouw, Swaab, and van Rijn

Date of Publication: February 25, 2022

“The significant improvement in facial emotion recognition, with large effect sizes, suggests that there are opportunities for positively supporting the development of social cognition in children with an extra X- or Y-chromosome, already at a very young age. This evidence based support is of great importance given the need for preventive and early training programs in children with SCT, aimed to minimize neurodevelopmental impact.”

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A review of neurocognitive functioning of children with sex chromosome trisomies

Article Title: A review of neurocognitive functioning of children with sex chromosome trisomies: Identifying targets for early intervention

Authors: Van Rijn, Urbanus, and Swaab

Date of Publication: July 2, 2019

“Results of the reviewed studies show that although traditionally, the focus has been on language and intelligence (IQ) in this population, recent studies suggest that executive functioning and social cognition may also be significantly affected already in childhood. These findings suggest that neuropsychological screening of children diagnosed with SCT should be extended, to also include executive functioning and social cognition. Knowledge about these neurocognitive risks is important to improve clinical care and help identify targets for early support and intervention programs to accommodate for the needs of individuals with SCT.”