"Expanding the Phenotype of Triple X Syndrome: A Comparison of Prenatal Versus Postnatal Diagnosis" —This cross-sectional study was published in the American Journal of Medical Genetics. It describes the diagnosis, physical aspects, medical problems, and neurodevelopmental features in a large cohort of females with 47, XXX. Click here.
Kathleen Erskine, a graduate student in the Joan H. Marks Graduate Program in Human Genetics at Sarah Lawrence College conducted a study to identify the important aspects of 47, XXX/ 3X/ Triple X/ Trisomy X to discuss with girls when they first learn about their Trisomy X diagnosis. The end result of this study is [...]
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Attention-Deficit Hyperactivity Disorder Symptoms in Children and Adolescents with Sex Chromosome Aneuploidy: XXY, XXX, XYY, and XXYY Tartaglia, Nicole R. MD; Ayari, Natalie BA; Hutaff-Lee, Christa PhD; Boada, Richard PhD Link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348431/pdf/nihms363084.pdf Please share this article with your healthcare providers and with other professionals (therapists, school support staff and administrators, etc.).
Kate Yandell Published: June 13, 2014 References: 1.) van Rijn S. et al. Genes Brain Behav. Epub ahead of print (2014) 2.) Bishop D.V. et al. Arch. Dis. Child 96, 954-959 (2011) Girls and boys born with an extra X chromosome both tend to have difficulties understanding the minds of others, but for different reasons than children [...]
By: Sophie van Rijn and Hanna Swaab Published: February 12, 2015 ABSTRACT Neuroimaging studies have shown that having an extra X chromosome is associated with abnormal structure and function of brain areas in the frontal lobe, which is crucially involved in executive functioning. However, there is little of knowledge of the type and severity of [...]
Dr. Sophie Van Rijn Click on the following link to view the video presentation: https://vimeo.com/130199302