Welcome to AXYS. We’re happy you are here.

AXYS, the Association for X and Y Chromosome Variations, is an advocacy, education and support organization for individuals with X and Y chromosome variations and their families. This includes those with Klinefelter syndrome (47,XXY), Trisomy X (47,XXX), 47,XYY, 48,XXYY, 48,XXXY and related genetic conditions.

The mission of AXYS is to help individuals with one or more extra X and/or Y chromosomes and their families to lead fuller, more productive lives. 

AXYS fulfills this mission through: 

  • Support geared to the needs of individuals, their families, and the professionals who serve them 

  • Education that provides current, scientifically accurate information to our constituents and to the public 

  • Promoting research that advances knowledge of the field 

  • Improving treatment options and access for those affected by the conditions

Welcome to AXYS. We’re happy you are here.

AXYS, the Association for X and Y Chromosome Variations, is an advocacy, education and support organization for individuals with X and Y chromosome variations and their families. This includes those with Klinefelter syndrome (47,XXY), Trisomy X (47,XXX), 47,XYY, 48,XXYY, 48,XXXY and related genetic conditions.

The mission of AXYS is to help individuals with one or more extra X and/or Y chromosomes and their families to lead fuller, more productive lives. 

AXYS fulfills this mission through: 

  • Support geared to the needs of individuals, their families, and the professionals who serve them 

  • Education that provides current, scientifically accurate information to our constituents and to the public 

  • Promoting research that advances knowledge of the field 

  • Improving treatment options and access for those affected by the conditions

Resources

Link to the Official AXYS YouTube Channel

Link to page with support groups for individuals with XXY, XYY, Trisomy X, XXYY, and other variations.

Link to CME (Continuing Medical Education) Courses page

Link to page with clinics for individuals with XXY, XYY, Trisomy X, XXYY, and other variations.

Link to page with research and clinical trials for those with XXY, XYY, Trisomy X, XXYY, and other variations.

Link to directory of professionals who specialize in XXY, XYY, Trisomy X, XXYY, and other variations.

Research

Exploring the Strengths of Students with X&Y Variations

"Children with sex chromosome aneuploidies (SCAs) are often characterized in the literature by limitations and pathologies related to the genetic diagnosis. This study aimed to broaden the SCA phenotype by describing parent reported character and [...]

A Klinefelter Update for Pediatricians

"Advances in the Interdisciplinary Care of Children with Klinefelter Syndrome"—This nearly 30-page story in the journal Advances in Pediatrics is directed at pediatricians and family physicians who treat children, and who may thus come across [...]

  • DNA strand

The Triple X Syndrome Phenotype

"Expanding the Phenotype of Triple X Syndrome: A Comparison of Prenatal Versus Postnatal Diagnosis" —This cross-sectional study was published in the American Journal of Medical Genetics. It describes the diagnosis, physical aspects, medical problems, and neurodevelopmental [...]

Exploring Klinefelter Syndrome

"The Impact of Living with Klinefelter Syndrome: A Qualitative Exploration of Adolescents and Adults" — This research article examines the medical, psychological, and social challenges that arise in individuals with 47,XXY as well as providing practical [...]

News

­

Link to AXYS News and Newsletters

Link to the AXYS Library of Research and Treatment Articles

­

Upcoming Events

Including support meetings, conferences, and webinars

Check back regularly for more AXYS webinars with X&Y Chromosome Variation experts!

Browse our previous webinars

The Twin Cities Support Group will be holding the next meeting on Monday, August 8 from 6 – 7pm on Zoom

Starting in September, meetings will be held once per month on the 2nd Monday of each month.

Calendar View: