Conclusions: Given that we link extra X chromosomes with structural language impairments and an extra Y chromosome with pragmatic language impairments, X/Y-aneuploidies may provide clues to genetic mechanisms contributing to idiopathic language impairment and autism spectrum disorders.
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Authors:  Nancy Raitano Lee, Gregory L. Wallace, Elizabeth I. Adeyemi, Katherine C. Lopez, Jonathan D. Blumenthal, Liv S. Clasen, and Jay N. Giedd

Child Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, MD, USA
Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, MD, USA