Article Title: Early Androgen Deficiency in Infants and Young Boys with 47,XXY Klinefelter Syndrome

Authors: Judith L. Ross, Carole Samango-Sprouse, Najiba Lahlou, Karen Kowal, Frederick F. Elder, and Andrew Zinn

Date of Publication: August 3, 2005

“The neonatal surge in testosterone was attenuated in our KS population. Thus, infants and young boys with KS have evidence of early testicular failure. The etiology of this failure and the clinical role of early androgen replacement require further study.”

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