Research conducted by Amy Turriff, MS, a certified genetic counselor at the National Eye Institute, Ophthalmic Genetics and Visual Function Branch at the National Institutes of Health in Bethesda, MD and a current member of AXYS’s Board of Directors, reveals that a significant percentage of 47,XXY individuals may be at risk of experiencing depression.  This is significant because it is well-documented that depression can have a major impact on an individual’s quality of life, physical health and overall mental health. Based on Turriff’s research, it appears very important that all XXY individuals be advised of this risk and have frequent and consistent clinical exams to identify possible depressive symptoms.

Turriff’s research was recently published in the scientific journal Genetics in Medicine (Genet Med 2011:13(11):966 –972) and an abstract is available at this link: //

The full article is available only to subscribers of the publication but AXYS felt an overview of this important research should be available to all.  To that end, Gary Glissman, chair of AXYS’s communication committee and a director on AXYS’s Board of Directors conducted an interview with Turriff to share her findings and help us all understand why this research study is so important for individuals who are XXY.