Article Title: Neural systems for social cognition in Klinefelter syndrome (47,XXY): evidence from fMRI

Authors: Sophie van Rijn, Hanna Swaab, Daan Baas, Edward de Haan, René S. Kahn, and André Aleman

Date of Publication: July 6, 2011

Klinefelter syndrome (KS) is a chromosomal condition (47, XXY) that may help us to unravel gene–brain behavior pathways to psychopathology. The phenotype includes social cognitive impairments and increased risk for autism traits. We used functional MRI to study neural mechanisms underlying social information processing. Eighteen nonclinical controls and thirteen men with XXY were scanned during judgments of faces with regard to trustworthiness and age.”

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