Reduced artery diameters in Klinefelter syndrome

//Reduced artery diameters in Klinefelter syndrome

Reduced artery diameters in Klinefelter syndrome

Article Title: Reduced artery diameters in Klinefelter syndrome

Authors: C. Foresta, N. Caretta, P. Palego, A. Ferlin, D. Zuccarello, A. Lenzi, R. Selice

Date of Publication: April 10, 2012

“Various epidemiological studies in relatively large cohorts of patients with Klinefelter syndrome (KS) described the increased morbidity and mortality in these subjects. Our aim was to study the structure and function of arteries in different districts to investigate in these subjects possible alterations. A total of 92 patients having non-mosaic KS, diagnosed in Centre for Human Reproduction Pathology at the University of Padova, and 50 age-matched healthy male controls were studied. Klinefelter syndrome subjects and controls evaluation included complete medical history, physical examination, measurement of concentrations of the reproductive hormones, lipidic and glycidic metabolism, AR function and sensitivity, ultrasound examinations (diameters, carotid intima-media thickness and brachial flow-mediated dilation) of brachial, common carotid and common femoral artery and abdominal aorta. Klinefelter syndrome patients showed significantly reduced artery diameters in all districts evaluated.”

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2018-09-28T11:52:31+00:00Categories: 47,XXY (Klinefelter)|