Testosterone Therapy for Individuals with Sex Chromosome Aneuploidies
Presentation slides from the 2017 AXYS Family Conference presentation:
Presented by Alan D. Rogol, MD PhD
Male Fertility in X & Y Variations
Presentation slides from the 2017 AXYS Family Conference presentation:
Male Fertility in X and Y Variations: Current State-of-the-Art and Future Implications (PDF)
Presented by Akanksha Mehta, MD MS
Metabolic Syndrome in 47,XXY
Presentation slides from the 2017 AXYS Family Conference presentation:
Metabolic Syndrome in 47,XXY (PDF)
Presented by Bahareh Michelle Schweiger, DO, MPH
Brain And Behavioral Development In Klinefelter Syndrome
Presentation slides from the 2017 AXYS Family Conference presentation:
Brain And Behavioral Development In Klinefelter Syndrome (PDF)
Presented by Alan Reiss, MD
Thinking About Starting Testosterone for XXY/XXYY/XXXY
Presentation slides from the 2017 AXYS Family Conference presentation:
Thinking About Starting Testosterone for XXY/XXYY/XXXY (PDF)
Presented by Shanlee Davis, MD, MSCS
The Challenges of Klinefelter’s
“The Klinefelter Syndrome: Current Management and Research Challenges”—From the scientific journal, Andrology, this article summarizes the concluding “Round Table Discussion” of the 2nd International Workshop on the Klinefelter Syndrome in Munster, Germany, March, 2016. Topics include syndrome characteristics, centers of competence for diagnosis and treatment, counseling, support groups, early screening, fertility, testosterone treatment, and basic research. Click here.
See also: “Speaker Abstracts from the 2nd International Workshop on Klinefelter Syndrome March 2016 Münster, Germany.”
Mortality in Patients with Klinefelter Syndrome in Britain: A Cohort Study
Article Title: Mortality in Patients with Klinefelter Syndrome in Britain: A Cohort Study
Authors: Anthony Swerdlow, Craig Higgins, Minouk Schoemaker, Alan Wright, and Patricia Jacobs
Date of Publication: December 1, 2005
“Patients diagnosed with Klinefelter syndrome have raised mortality from several specific causes. This may reflect hormonal and genetic mechanisms.”
An Extra X or Y Chromosome: Contrasting the Cognitive and Motor Phenotypes in Childhood in Boys with 47,XYY Syndrome or 47,XXY Klinefelter Syndrome
Article Title: An extra X or Y chromosome: contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome
Authors: Judith L. Ross, Martha P.D. Zeger, Harvey Kushner, Andrew R. Zinn, and David P. Roeltgen
Date of Publication: 2009
“The results from these large XYY and KS cohorts have important neurocognitive and educational implications. From the neurocognitive standpoint, the presenting findings afford an opportunity to gain insights into brain development in boys with XYY and those with KS. From the educational standpoint, it is critical that boys with XYY or KS receive appropriate educational interventions that target their specific learning challenges. These findings also provide important information for counseling clinicians and families about these disorders.”
Neurocognitive research on 47,XXY
Title: Neurobehavioral and Psychosocial Issues in Klinefelter Syndrome
Authors: Daniel H. Geschwind and Elisabeth Dykens
Date of Publication: 2004
This is one of the “gold standard” research articles on 47,XXY neurocognitive implications. It contains pretty intense medical terminology but it would be recognized as excellent resource/reference material by physicians, educators, the courts, etc. It should help parents and others understand there are absolutely biological issues involved with potential problem behaviors that may be happening with someone that is 47,XXY.
Comparing 47,XXY and 47,XYY boys
Title: An extra X or Y chromosome: contrasting the cognitive and motor phenotypes in childhood in boys with 47,XYY syndrome or 47,XXY Klinefelter syndrome
Authors: Judith L. Ross, Martha P.D. Zeger, Harvey Kushner, Andrew R. Zinn, and David P. Roeltgen
Date of Publication: December 2009
A research article on comparing the similarities and differences in boys with 47,XXY and 47,XYY from a neurocognitive testing standpoint.