You searched for Buy generic fast shipping Y buy online☘️🔶⣻ www.Getmaple.store ⣻🔶☘️ 25 Mg price in india Can you buy over counter in uk/page/48/Stella_Boeckman@rush.edu/page/11/Stella_Boeckman@rush.edu - Page 46 of 52 - The Association for X and Y Chromosome Variations

Testicular size and shape of 47,XYY and 47,XXY men in a double-blind, double-matched population survey

Article Title: Testicular size and shape of 47,XYY and 47,XXY men in a double-blind, double-matched population survey

Author: E. Boisen

Date of Publication: November 1979

“This paper reports the testicular size and shape of 12 men with 47,XYY, 14 men with 47,XXY, and 52 matched controls with 46,XY. The abnormal karyotypes were identified in a systematic population search for XYY and XXY men. The subjects and their matched controls were examined in a double-blind fashion. The testes of the XYY men showed no significant differences from those of their XY controls for volume or shape. This indicates that previous reports of abnormal testes in XYYs reflect selection and publication bias and do not provide an accurate description of the condition of 47,XYY men’s testicles. As expected, the testes of the XXY men were significantly smaller than those of their XY controls, and there was also a difference in shape. However, the mean size in this sample of XXYs was larger than in previous reports on Klinefelter syndrome patients, indicating that previous reports on XXYs, identified in clinics for male hypogonadism and other institutions, also suffered from selection bias.”

Rick Frith2018-08-17T16:39:54-04:00Categories: 47,XXY (Klinefelter), 47,XYY|

48,XXYY, 48,XXXY and 49,XXXXY Syndromes: Not Just Variants of Klinefelter Syndrome

Article Title: 48,XXYY, 48,XXXY and 49,XXXXY syndromes: not just variants of Klinefelter syndrome

Authors: Tartaglia, Ayari, Howell, D’Epagnier, Zeitler

Date of Publication: April 9, 2011

“Sex chromosome tetrasomy and pentasomy conditions occur in 1:18,000-1:100,000 male births. While often compared with 47,XXY/Klinefelter syndrome because of shared features including tall stature and hypergonadotropic hypogonadism, 48,XXYY, 48,XXXY and 49,XXXXY syndromes are associated with additional physical findings, congenital malformations, medical problems and psychological features.”

Rick Frith2018-08-17T16:45:49-04:00Categories: 48,XXYY, Other Variations|Tags: 49XXXXY|

FDA Panel Rejects New Oral Testosterone Replacement Drug

Article Title: FDA Panel Rejects New Oral Testosterone Replacement Drug

Author: Larry Hand

Date of Publication: September 18, 2014

A combined US Food and Drug Administration (FDA) advisory committee has voted against recommending approval of oral testosterone undecanoate (TU) gel capsules as testosterone-replacement therapy (TRT).

In a joint session today of the Bone, Reproductive and Urologic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, panelists voted 12 to 8, with 1 abstention, that there is insufficient evidence to conclude that the testosterone prodrug is effective. They voted 18 to 3 that the overall benefit/risk profile was not acceptable to support approval.

Rick Frith2018-08-17T16:51:03-04:00Categories: 47,XXY (Klinefelter)|

Executive Function: What Does It Mean? Why Is It Important? How Can We Help?

Article Title: Executive Function: What Does It Mean? Why Is It Important? How Can We Help?

Author: Mark Katz, PhD

Date of Publication: Summer 2014

“The term ‘executive function’ is being used throughout educational circles, from preschool classrooms to university research labs. But what exactly is it and how does it influence school success?

To complete tasks, reach goals, solve problems, and successfully navigate our social world, we rely on our executive function, 1. a family of mental processes that includes working memory; skills in organization, planning, and time management; and self-control and emotional self-regulation, among others. 2. While we typically see these mental processes discussed separately, they actually work in harmony. In fact, it’s our ability to successfully synchronize these processes that allows us to navigate the world. Experts in the field have used different metaphors to describe this process and its coordination: our brain’s orchestra conductor, air traffic control system, or chief executive officer.

Executive function is getting a great deal of attention lately for good reason. How well it works is an important predictor of who will succeed in school and who will not. And if we can predict problems of executive function, we can prevent them.”

Rick Frith2018-08-17T17:00:02-04:00Categories: All Variations|

Individualized Education Program (IEP): Summary, Process, and Practical Tips

Article Title: Individualized Education Program (IEP): Summary, Process, and Practical Tips

Author: Goodwin Procter, Autism Speaks

Date of Publication: August 19, 2011

After months of research, a team of lawyers at Goodwin Procter LLP has generously put together a helpful guide to help families understand the IEP process as their loved ones head back to school: Individualized Education Program (IEP): Summary, Process and Practical Tips. This 26 page guide contains an IEP timeline and clearly lays out the steps to take throughout the IEP process. The guide also includes lots of tips, resources, and answers to FAQs.

Rick Frith2022-03-15T13:38:38-04:00Categories: All Variations|Tags: Education|

IEP and Lesson Plan Development Handbook

Article Title: IEP and Lesson Plan Development Handbook of Specially Designed Instruction and Supplementary Aids and Services

Authors: Kentucky Special Education Cooperatives and Kentucky Department of Education

Date of Publication: August 2003

“In designing an Individual Education Program (IEP) for a student, the ARC must determine specific instructional strategies that teachers must use and the supplementary aids and services that the student needs in order for the student to have access to the Program of Studies (i.e., the general program).

This handbook is one resource that provides some examples of Specially Designed Instruction (SDI) and Supplementary Aids and Services (SAS) that might be used to support the student’s goals, benchmarks, and objectives on his/her IEP.”

Rick Frith2018-08-25T16:25:36-04:00Categories: All Variations|

The Learning Needs of Boys With KS – Information for Teachers & Parents

Article Title: The Learning Needs of Boys With KS – Information for Teachers & Parents

Authors: Paul Collingridge, Klinefelter’s Syndrome Association (UK)

Date of Publication: 2004

“Recent years have seen the tide turning in the ways that boys with Klinefelter’s Syndrome (KS) have settled down at school, this is reflected in the statistics of the Klinefelter’s Syndrome Association survey which pointed out that whilst virtually no adults had attended special schools as children, the figure had risen to around 1 in 3 by 1999. There is still a long way to go; many parents still feel the frustration of battling out for help against cash-strapped education authorities, and many teachers long for insight into the minds of boys with complex needs.”

Rick Frith2018-09-06T12:44:12-04:00Categories: 47,XXY (Klinefelter)|

Long-Term Testosterone Therapy Does Not Increase the Risk of Prostate Cancer

Article Title: Long-term testosterone therapy does not increase the risk of prostate cancer

Author: Elsevier Health Sciences

Date of Publication: November 25, 2014

“Testosterone (T) therapy is routinely used in men with hypogonadism, a condition in which diminished function of the gonads occurs. Although there is no evidence that T therapy increases the risk of prostate cancer (PCa), there are still concerns and a paucity of long-term data. In a new study in The Journal of Urology^®, investigators examined three parallel, prospective, ongoing, cumulative registry studies of over 1,000 men. Their analysis showed that long-term T therapy in hypogonadal men is safe and does not increase the risk of PCa.

Rick Frith2018-08-25T16:31:51-04:00Categories: 47,XXY (Klinefelter)|

Management of Klinefelter syndrome during transition

Article Title: Management of Klinefelter syndrome during transition

Authors: I. Gies, D. Unuane, B. Velkeniers, J. De Schepper

Date of Publication: May 2014

“Medical treatment during transition into adulthood is focused on fertility preservation and testosterone replacement therapy in the case of hypo-androgenism, and alleviation of current or future consequences of testicular fibrosis. However, more research is needed to determine the need for pro-active testosterone treatment in adolescence, as well as the conditions for an optimal testosterone replacement and sperm retrieval in adolescents and young men with KS. Furthermore, screening for associated diseases such as metabolic syndrome, autoimmune diseases, thyroid dysfunction, and malignancies is warranted during this period of life. The practical medical management during transition and, more specifically, the role of the endocrinologist are discussed in this article.”

Rick Frith2018-08-25T16:41:11-04:00Categories: 47,XXY (Klinefelter)|

Vulnerability for autism traits in boys & men with an extra X chromosome (47,XXY): the mediating role of cognitive flexibility

Article Title: Vulnerability for autism traits in boys and men with an extra X chromosome (47,XXY): the mediating role of cognitive flexibility

Authors: Sophie van Rijn, Marit Bierman, Hilgo Bruining, Hanna Swaab

Date of Publication: August 11, 2012

“Our findings suggest that KS can be associated with dysfunctions in mental flexibility, and that individuals with more mental flexibility problems also have more autism traits. This insight is relevant for diagnosis, prevention and treatment of severe problems in individuals with KS. Implications also extend beyond this specific syndrome. As executive dysfunctions in KS have also been linked to ADHD symptoms and thought disorder, this could be a shared mechanism contributing to overlap in symptoms and comorbidity between different psychiatric conditions.”

Rick Frith2018-08-25T16:50:06-04:00Categories: 47,XXY (Klinefelter)|