Monthly Archives: August 2017

//August

Quality of Life in Men with Klinefelter Syndrome: The Impact of Genotype, Health, Socioeconomics, and Sexual Function

Article Title: Quality of life in men with Klinefelter syndrome: the impact of genotype, health, socioeconomics, and sexual function

Authors: Anne Skakkebæk, MD, PhD, Philip J. Moore, MS, Simon Chang, MD, Jens Fedder, MD, PhD, and Claus H. Gravholt, MD, DMSc

Date of Publication: July 2017

“…relatively little attention has been paid to QoL in men with KS, or the factors that may determine it. In two studies to date, boys and men with KS were found to have a lower QoL than non-KS males in population-based samples. KS phenotype severity was also negatively associated with QoL among boys. In a third study, KS status was correlated with lower psychosocial well-being, which was associated with lower levels of employment and social support, and greater disease severity.”

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2018-09-08T20:45:22+00:00Categories: 47,XXY (Klinefelter)|

The Role of Genes, Intelligence, Personality, and Social Engagement in Cognitive Performance in Klinefelter Syndrome

Article Title: The role of genes, intelligence, personality, and social engagement in cognitive performance in Klinefelter syndrome

Authors: Anne Skakkebæk, Philip J. Moore, Anders Degn Pedersen, Anders Bojesen, Maria Krarup Kristensen, Jens Fedder, Peter Laurberg, Jens Michael Hertz, John Rosendahl Østergaard, Mikkel Wallentin, Claus Højbjerg Gravholt

Date of Publication: December 2016

“The determinants of cognitive deficits among individuals with Klinefelter syndrome (KS) are not well understood. This study was conducted to assess the impact of general intelligence, personality, and social engagement on cognitive performance among patients with KS and a group of controls matched for age and years of education.”

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2018-09-09T10:06:45+00:00Categories: 47,XXY (Klinefelter)|

XXY Update – Fall, 2017

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In case you have not had a chance to visit the AXYS website lately, several new research papers have been added in the library that you may want to review and also share with your health care providers and others. Two of these articles involve research by Dr. Claus Gravholt and his team at the Department of Endocrinology and Internal Medicine at Aarhus University Hospital in Denmark. This multidisciplinary clinic specializes in treating XXY individuals over the age of 15 and is one of the few clinics in the world that has that distinction. They see more than 400 adult patients with KS and have published a number of excellent research papers in the past based on their experiences.

Their latest publications focus on cognitive performance and quality of life issues associated with KS adults and they bring out many important points, including:

    1. Adult issues related to neurocognitive challenges are complex, difficult and do not receive adequate research attention or effective care.
    2. There are very few places in the world that provide expert multidisciplinary treatment for XXY adults.
    3. Most KS adults have difficulty finding skilled, effective health care from health professionals that are aware of current research in KS.

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2017-09-05T20:08:59+00:00Categories: 47,XXY (Klinefelter)|