Search Site
Helpline: 1‑267‑338‑4262 | info@genetic.org
Stay Connected
AXYS - The Association for X&Y Chromosome Variations
Donate Now
Helpline: 1‑267‑338‑4262 | info@genetic.org
Stay Connected
Donate Now

Quality of life

Home » Library » Quality of life

Association between domains of quality of life and patients with Klinefelter syndrome: a systematic review

Article Title: Association between domains of quality of life and patients with Klinefelter syndrome: a systematic review

Authors: Mehmet, Gillard, Jayasena, and Llahana

Date of Publication: May 31, 2022

“This is the first evidence synthesis of QoL in men with KS. Current evidence suggests that combined physical and psychological impairments affect men with KS who also experience impairments in relationships and independence in society. Further research is needed to identify factors that influence the QoL in men with KS.”

Read more

2022-10-12T12:34:50-04:00Categories: 47,XXY (Klinefelter)|Tags: |

The Lived Experience of Klinefelter Syndrome: A Narrative Review of the Literature (Psychosocial and Quality of Life Impact)

Article Title: The Lived Experience of Klinefelter Syndrome: A Narrative Review of the Literature

Authors: Hanna, Cheetham, Fearon, Herbrand, Hudson, McEleny, Quinton, Stevenson, and Wilkes

Date of Publication: November 26, 2019

“This review examines the existing psychosocial evidence around the impact of KS, exploring what we know about KS and its relevance for health care for this group.”

Read more

2020-02-18T11:01:00-05:00Categories: 47,XXY (Klinefelter)|Tags: |

Quality of Life in Men with Klinefelter Syndrome: The Impact of Genotype, Health, Socioeconomics, and Sexual Function

Article Title: Quality of life in men with Klinefelter syndrome: the impact of genotype, health, socioeconomics, and sexual function

Authors: Anne Skakkebæk, MD, PhD, Philip J. Moore, MS, Simon Chang, MD, Jens Fedder, MD, PhD, and Claus H. Gravholt, MD, DMSc

Date of Publication: July 2017

“…relatively little attention has been paid to QoL in men with KS, or the factors that may determine it. In two studies to date, boys and men with KS were found to have a lower QoL than non-KS males in population-based samples. KS phenotype severity was also negatively associated with QoL among boys. In a third study, KS status was correlated with lower psychosocial well-being, which was associated with lower levels of employment and social support, and greater disease severity.”

Read More

2020-02-18T10:48:28-05:00Categories: 47,XXY (Klinefelter)|Tags: |

Phenotype and Adverse Quality of Life in Boys with Klinefelter Syndrome

Article Title: Phenotype and Adverse Quality of Life in Boys with Klinefelter Syndrome

Authors: S. Close, I. Fennoy, A. Smaldone, N. Reame

Date of Publication: June 22, 2015

“To characterize associations among psychosocial well-being, physical phenotype, and sex hormones in a sample of youth with Klinefelter syndrome (KS). We hypothesized that KS physical traits (phenotype) are associated with adverse psychosocial health measures and that testosterone levels are associated with adverse psychosocial health…Depending on the degree of phenotypic abnormality, boys with KS may be at risk for impaired QOL. Testosterone levels were not shown to influence psychosocial health. The Klinefelter Phenotype Index Scale may be a useful tool to characterize KS features in boys.”

Read more

2020-02-18T10:49:37-05:00Categories: 47,XXY (Klinefelter)|Tags: |
Go to Top