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Guidebook: FREE Spanish Translation

A Spanish-language translation of Virginia Cover’s essential guidebook, “Living with Klinefelter Syndrome (47,XXY) Trisomy X (47,XXX) and 47,XYY: A Guide for Families and Individuals Affected by Extra X and Y Chromosomes,” is available as a FREE download.

Una traducción en español del libro guía esencial de Virginia Cover, “Living with Klinefelter Syndrome (47,XXY) Trisomy X (47,XXX) and 47,XYY: A Guide for Families and Individuals Affected by Extra X and Y Chromosomes,” está disponible como una descarga gratuita.

CLICK AQUÍ PARA DESCARGAR LA TRADUCCIÓN ESPAÑOLA GRATIS

Rick Frith2018-08-02T17:03:26-04:00Categories: All Variations|

Exercising the Mind to Treat Attention Deficits

Article Title: Exercising the Mind to Treat Attention Deficits

Author: Daniel Goleman

Date of Publication: May 12, 2014

“Now a growing stream of research suggests that strengthening this mental muscle, usually with exercises in so-called mindfulness, may help children and adults cope with attention deficit hyperactivity disorder and its adult equivalent, attention deficit disorder.”

Rick Frith2018-08-02T17:15:46-04:00Categories: All Variations|

Klinefelter’s Syndrome (Karyotype 47,XXY) and Schizophrenia-spectrum Pathology

Article Title: Klinefelter’s syndrome (karyotype 47, XXY) and schizophrenia-spectrum pathology

Authors: Sophie van Rijn, MSc; André Aleman, PhD; Hanna Swaab, PhD; and René Kahn, PhD, MD

Date of Publication: November 2006

“Klinefelter’s syndrome, characterised by a 47, XXY chromosomal pattern, has largely been associated with physical abnormalities. Here, we report high levels of schizophrenia-spectrum pathology in 32 men with this syndrome in comparison with 26 healthy controls. This may have implications for treatment of Klinefelter’s syndrome and suggests that the X chromosome may be involved in the aetiology of schizophrenia.”

Rick Frith2018-08-02T17:25:38-04:00Categories: 47,XXY (Klinefelter)|

When to Ask Male Adolescents to Provide Semen Sample for Fertility Preservation?

Article Title: When to ask male adolescents to provide semen sample for fertility preservation?

Authors: Peter N. Schlegel et al

Date of Publication: March 2014

“It is appropriate to consider a request for semen specimens by masturbation from teenagers at one year and six months after the onset of puberty; the onset age of puberty plus 1.5 years is an important predictor of ejaculation and sample collection for cryopreservation.”

Rick Frith2023-01-06T12:12:57-05:00Categories: 47,XXY (Klinefelter)|Tags: Fertility|

Genetic Evaluation of Male Infertility

Article Title: Genetic evaluation of male infertility

Author: Matthew S. Wosnitzer

Date of Publication: March 2014

“Men with severe oligospermia (<5 million sperm/mL ejaculate fluid) or azoospermia should receive genetic testing to clarify etiology of male infertility prior to treatment. Categorization by obstructive azoospermia (OA) or non-obstructive azoospermia (NOA) is critical since genetic testing differs for the former with normal testicular function, testicular volume (~20 mL), and follicle-stimulating hormone (FSH) (1-8 IU/mL) when compared to the latter with small, soft testes and increased FSH.”

Rick Frith2020-03-16T12:54:09-04:00Categories: 47,XXY (Klinefelter)|Tags: Fertility|

Medical Treatment of Male Infertility

Article Title: Medical treatment of male infertility

Authors: Ali A. Dabaja, Peter N. Schlegel

Date of Publication: March 2014

“The majority of male infertility is idiopathic. However, there are multiple known causes of male infertility, and some of these causes can be treated medically with high success rates. In cases of idiopathic or genetic causes of male infertility, medical management is typically empirical; in most instances medical therapy represents off-label use that is not specifically approved by the FDA. Understanding the hypothalamic-pituitary-gonadal (HPG) axis and the effect of estrogen excess is critical for the assessment and treatment of male infertility.”

Rick Frith2020-03-16T12:56:36-04:00Categories: 47,XXY (Klinefelter)|Tags: Fertility|

Surgical Management of Male Infertility: An Update

Article Title: Surgical management of male infertility: an update

Authors: Monica Velasquez, Cigdem Tanrikut

Date of Publication: March 2014

“Male factor infertility is common, affecting 7% of the total population and up to half of couples who are trying to conceive. Various surgical and reconstructive options allow biological paternity depending on the etiology of the male factor issues. This article describes historical treatments and newer approaches, discussing the role for traditional open surgery, microsurgery and robotic surgery, as well as interventional radiologic procedures in the management of male infertility.”

Rick Frith2020-03-16T12:55:49-04:00Categories: 47,XXY (Klinefelter)|Tags: Fertility|

Neural systems for social cognition in Klinefelter syndrome (47,XXY)

Article Title: Neural systems for social cognition in Klinefelter syndrome (47,XXY): evidence from fMRI

Authors: Sophie van Rijn, Hanna Swaab, Daan Baas, Edward de Haan, René S. Kahn, and André Aleman

Date of Publication: July 6, 2011

“Klinefelter syndrome (KS) is a chromosomal condition (47, XXY) that may help us to unravel gene–brain behavior pathways to psychopathology. The phenotype includes social cognitive impairments and increased risk for autism traits. We used functional MRI to study neural mechanisms underlying social information processing. Eighteen nonclinical controls and thirteen men with XXY were scanned during judgments of faces with regard to trustworthiness and age.”

Rick Frith2018-08-05T14:20:34-04:00Categories: 47,XXY (Klinefelter)|

Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy

Article Title: Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy

Authors: Prasanth N. Surampudi, Christina Wang, and Ronald Swerdloff

Date of Publication: December 2011

“Hypogonadism in older men is a syndrome characterized by low serum testosterone levels and clinical symptoms often seen in hypogonadal men of younger age. These symptoms include decreased libido, erectile dysfunction, decreased vitality, decreased muscle mass, increased adiposity, depressed mood, osteopenia, and osteoporosis. Hypogonadism is a common disorder in aging men with a significant percentage of men over 60 years of age having serum testosterone levels below the lower limits of young male adults.”

Rick Frith2022-02-16T12:52:30-05:00Categories: 47,XXY (Klinefelter)|Tags: Testosterone treatment|

Klinefelter Syndrome – A Clinical Update

Article Title: Clinical review: Klinefelter syndrome – a clinical update

Authors: K.A. Groth, A. Skakkebæk, C. Høst, C.H. Gravholt, A. Bojesen

Date of Publication: November 1, 2012

“Recently, new clinically important information regarding Klinefelter syndrome (KS) has been published. We review aspects of epidemiology, endocrinology, metabolism, body composition, and neuropsychology with reference to recent genetic discoveries.”

Rick Frith2018-09-05T14:26:29-04:00Categories: 47,XXY (Klinefelter)|